Amificas, Inc.

PVPI SANAQ®

General information

Povidone–Iodine is a complex of iodine with polyvinyl pyrrolidone that is highly effective against agents causing disease in man, lower animals, and plants, it retains the rapid, broad– spectrum action of elemental iodine against bacteria, viruses, funghi, spores, protozoa, and yeasts. It has also been shown to be effective in the control of some insects, helminthes, and nematodes.

On the other hand, Povidone is safer and easier to use than classical preparations of the halogen. This organic iodine complex has a low systemic toxicity and is essentially non–irritating to mammalian tissue. It is nonsensitizing and does not cause severe pain when applied to wounds or mucous membranes.

Moreover, Povidone–Iodine forms films that protect open wounds but are water–washable and will not permanently stain skin, natural fibers, or hard surfaces. It is exceptionally easy to formulate because it is soluble in water as well as in organic solvents, such as alcohols. It is equally adaptable for use in powder, solution, lotion, cream, or spray vehicles.

Physical and Chemical Properties

Povidone–Iodine is a stable chemical complex of polyvinyl pyrrolidone (pvp) and elemental iodine. It contains not less than 9.0 percent and not more than 12.0 percent of available iodine. It is soluble in water and in alcohol; Practically insoluble in chloroform, in carbon tetrachloride, in ether, in solvent hexane, an in acetone.

Incompatibility

1. pH: Systems incorporating, Povidone–Iodine should be on the side to prevent dissociation of diatomic iodine. Alkaline solutions, including ammonia, and reducing agents lower the antiseptic action.
2. Plastic, wood, or stainless steel may be used for measuring Povidone–Iodine. It should be noted that aqueous solutions containing 2% available iodine will corrode silver within two hours, while stainless steel is unaffected.